PARD6A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75310A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using PARD6A Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PARD6A Polyclonal Antibody at dilution 1:60
Product Name
PARD6A Polyclonal Antibody
Catalog Number
RD75310A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen Information
Immunogen
Recombinant protein of human PARD6A
Swissprot
Q9NPB6
Synonyms
0710008C04Rik2610010A15RikPar 6 partitioning defective 6 C elegans homolog alphaPar 6 partitioning defective 6 homolog alphaPar 6 partitioning defective 6 homolog alpha C elegansPAR 6APAR-6 alphaPAR-6par-6 family cell polarity regulator alphaPAR-
Gene Accession
BC015626
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.