PARL Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD84971A
Western blot analysis of extracts of various cell lines using PARL Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of U2OS cells using PARL Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
PARL Polyclonal Antibody
Catalog Number
RD84971A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.
Immunogen Information
Immunogen
Recombinant fusion protein of human PARL (NP_001032728.1).
Gene ID
55486
Swissprot
Q9H300
Synonyms
PARLPRO2207PSARLPSARL1PSENIP2RHBDS1
Calculated MW
36 kDa/42 kDa
Observed MW
49 kDa
Applications
Reactivity
Human
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas