PARP1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78731A
Western Blot analysis of Hela, K562 and Jurkat cell using PARP1 Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human ovarian cancer using PARP1 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human esophagus cancer using PARP1 Polyclonal Antibody at dilution of 1:40
Product Name
PARP1 Polyclonal Antibody
Catalog Number
RD78731A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Immunogen Information
Immunogen
Synthetic peptide of human PARP1
Swissprot
P09874
Synonyms
ADP-ribosyltransferase diphtheria toxin-like 1ADPRT 1ADPRTADPRT1APOPAINARTD1NAD(+) ADP-ribosyltransferase 1PARPPARP-1PARP1PARP1Poly [ADP-ribose] polymerase 1Poly ADP ribose polymerase 1Poly[ADP-ribose] synthase 1PPOLSCA1
Calculated MW
113 kDa
Gene Accession
NP_001609.2
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.