This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations
Immunogen Information
Immunogen
Synthetic peptide of human PAX1
Swissprot
P15863
Synonyms
HUP48OTTHUMP00000030407Paired box 1Paired box gene 1Paired box protein Pax 1Paired box protein Pax-1Paired domain gene HuP48PAX 1Pax1PAX1
Calculated MW
55 kDa
Gene Accession
NP_006183
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4