PCBD1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253015A
Western blot analysis of Human fetal liver tissue lysate using PCBD1 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:90(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:90(×200)
Product Name
PCBD1 Polyclonal Antibody
Catalog Number
RD253015A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Fusion protein of human PCBD1
Swissprot
P61457
Synonyms
4 alpha hydroxy tetrahydropterin dehydratase4-alpha-hydroxy-tetrahydropterin dehydratase6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of
Calculated MW
12 kDa
Observed MW
Refer to figures
Gene Accession
BC006324
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:80-1:400, ELISA 1:5000-1:10000
Concentration
1.62 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.