PCK1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD82487A
Western blot analysis of extracts of various cell lines using PCK1 Polyclonal Antibody.
Product Name
PCK1 Polyclonal Antibody
Catalog Number
RD82487A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Immunogen Information
Immunogen
A synthetic peptide of human PCK1 (NP_002582.3).
Gene ID
5105
Swissprot
P35558
Synonyms
PCK1PEPCK-CPEPCK1PEPCKC
Calculated MW
34 kDa/69 kDa
Observed MW
69 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas