PCLAF Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD253019A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using PCLAF Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PCLAF Polyclonal Antibody at dilution of 1:60(×200)
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Overview

Circle
Product Name
PCLAF Polyclonal Antibody
Catalog Number
RD253019A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

Immunogen Information

Circle
Immunogen
Fusion protein of human PCLAF
Swissprot
Q15004
Synonyms
HCV NS5A transactivated protein 9HCV NS5A-transactivated protein 9Hepatitis C virus NS5A transactivated protein 9Hepatitis C virus NS5A-transactivated protein 9KIAA0101L5NS5 ATP9NS5ATP9OEATC 1OEATCOEATC-1OEATC1Overexpressed in anaplastic thyr
Gene Accession
BC005832

Applications

Circle
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.08 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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