PD-1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86756A
Western blot analysis of extracts of various cell lines using PD-1/CD279 Polyclonal Antibody at 1:1000 dilution.
Immunofluorescence analysis of human tonsil cells using PD-1/CD279 Polyclonal Antibody at dilution of 1:150 (40x lens). Blue: DAPI for nuclear staining.
Product Name
PD-1 Polyclonal Antibody
Catalog Number
RD86756A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Immunogen Information
Immunogen
A synthetic peptide of human PD-1
Gene ID
5133
Swissprot
Q15116
Synonyms
PDCD1CD279PD-1PD1SLEB2hPD-1hPD-lhSLE1
Calculated MW
29kDa
Observed MW
29kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas