PDCD4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252165A
Western blot analysis of LOVO cell lysate using PDCD4 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PDCD4 Polyclonal Antibody at dilution of 1:35(×200)
Product Name
PDCD4 Polyclonal Antibody
Catalog Number
RD252165A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation,progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.
Immunogen Information
Immunogen
Fusion protein of human PDCD4
Swissprot
Q53EL6
Synonyms
Death up-regulated gene proteinDugH731Ma3MGC33046MGC33047Neoplastic transformation inhibitorNeoplastic transformation inhibitor proteinNuclear antigen H731Nuclear antigen H731 likeNuclear antigen H731 like proteinNuclear antigen H731-likePDCD
Calculated MW
52 kDa
Observed MW
Refer to figures
Gene Accession
BC026104
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas