The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human PDE4A
Swissprot
P27815
Synonyms
5''-cyclic phosphodiesterase 4AcAMP specific phosphodiesterasecAMP-specific 3''cAMP-specific 3'5'-cyclic phosphodiesterase 4ADPDE2dunce like phosphodiesterase E2PDE 4APDE4PDE46PDE4APDE4APDE4A11Phosphodiesterase 4Aphosphodiesterase 4A cAMP sp
Calculated MW
98 kDa
Gene Accession
NP_001104777
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4