The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human PDE4C
Gene ID
5143
Swissprot
Q08493
Synonyms
PDE4CDPDE1PDE21
Calculated MW
22kDa/27kDa/42kDa
Observed MW
43kDa
Applications
Reactivity
Human,Rat
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:400
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.