PDE5A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79219A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PDE5A Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PDE5A Polyclonal Antibody at dilution 1:50
Product Name
PDE5A Polyclonal Antibody
Catalog Number
RD79219A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Immunogen Information
Immunogen
Synthetic peptide of human PDE5A
Swissprot
O76074
Synonyms
5''-cyclic phosphodiesteraseCGB PDECGB-PDECGBPDEcGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterasecGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterasecGMP binding cGMP specific phosphodiesterasecGMP binding/cGMP speci
Gene Accession
NP_001074
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.