Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' is an enzyme that in humans is encoded by the PDE6C gene. This gene encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4).
Immunogen Information
Immunogen
Synthetic peptide of human PDE6C
Swissprot
P51160
Synonyms
5''-cyclic phosphodiesterase subunit alpha''cGMP phosphodiesterase 6CCOD4Cone cGMP specific 3' 5' cyclic phosphodiesterase subunit alpha'Cone cGMP-specific 3''PDE 6CPDE6 alpha primePDE6 alpha'PDE6CPDE6CPDEA2Phosphodiesterase 6C cGMP specific co
Calculated MW
99 kDa
Gene Accession
NP_006195
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4