PDX1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78613A
Western Blot analysis of Hela and Jurkat cell using PDX1 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human colon cancer using PDX1 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human esophagus cancer using PDX1 Polyclonal Antibody at dilution of 1:30
Product Name
PDX1 Polyclonal Antibody
Catalog Number
RD78613A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Immunogen Information
Immunogen
Synthetic peptide of human PDX1
Swissprot
P52945
Synonyms
Glucose sensitive factorGlucose-sensitive factorGSFIDX 1IDX-1IDX1Insulin promoter factor 1Insulin promoter factor 1 homeodomain transcription factorInsulin upstream factor 1IPF 1IPF-1IPF1Islet/duodenum homeobox 1Islet/duodenum homeobox-1IUF
Calculated MW
31 kDa
Gene Accession
NP_000200
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:15-1:50
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.