CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
Immunogen Information
Gene ID
3687
Swissprot
P20702
Synonyms
Integrin alpha-XItgaxCD11 antigen-like family member CLeukocyte adhesion receptor p150+95CD11c
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
PE/AF594
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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