For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30730F
Human peripheral blood mononuclear cells are stained with APC Anti-Human CD45RO Antibody and PE/AF 594 Anti-Human CD123 Antibody[HI12H7] (Left). Mononuclear cells are stained with APC Anti-Human CD45RO Antibody and PE/AF 594 Mouse IgG1, κ Isotype Control (Right).
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Immunogen Information
Synonyms
IL-3RαIL-7Receptoralpha
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
PE/AF594
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Do not freeze.
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