Human peripheral blood mononuclear cells are stained with APC Anti-Human CD45RO Antibody and PE Anti-Human CD123 Antibody[HI12H7] (Left). Mononuclear cells are stained with APC Anti-Human CD45RO Antibody and PE Mouse IgG1, κ Isotype Control (Right).
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Immunogen Information
Synonyms
IL-3RαIL-4Receptoralpha
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
PE
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Do not freeze.