For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD22127F
Human peripheral blood lymphocytes are stained with Anti-Human CD25 Monoclonal Antibody(PE Conjugated) and Anti-Human CD4 Monoclonal Antibody(APC Conjugated)(Left). lymphocytes stained with Anti-Human CD4 Monoclonal Antibody(APC Conjugated) and Mouse IgG2a, κ Isotype Control(PE Conjugated)(Right) are used as control.
CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor α chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor β (CD122) and common γ chains (CD132) to form the high affinity IL-2R complex.