PE Anti-Human CD45RO Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD21719F
Human peripheral blood lymphocytes are stained with Anti-Human CD45RO Monoclonal Antibody(PE Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Product Name
PE Anti-Human CD45RO Antibody
Catalog Number
RD21719F
Clonality
Monoclonal
Isotype
Mouse IgG2a, κ
Host
Mouse
Background
CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
Immunogen Information
Gene ID
5788
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
PE
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.