Human peripheral blood lymphocytes are stained with APC Anti-human CD19 Antibody and PE Anti-Human CD5 Antibody[5D7] (Left). Lymphocytes are stained with APC Anti-human CD19 Antibody and PE Mouse IgG1, κ Isotype Control (Right).
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.