For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD21709F
PMA and ionomycin-stimulated (4h) Jurkat cells are stained with Anti-Human CD69 Monoclonal Antibody(PE Conjugated)(filled gray histogram) or Mouse IgG1, κ Isotype Control(PE Conjugated)(empty black histogram).
CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.
Immunogen Information
Gene ID
969
Swissprot
Q07108
Synonyms
Early activation antigen CD69Activation inducer moleculeAIMEA1MLR-3
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
PE
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.