C57BL/6 murine splenocytes are stained with Anti-Mouse CD16/32 Monoclonal Antibody(PE Conjugated)[Used at 0.2 μg/106 cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
Immunogen Information
Gene ID
14130 ,14131
Swissprot
P08508,P08101
Synonyms
CD16a/bCD32CD32A/BFc fragment of IgG low affinity IIa/b receptorFc fragment of IgG low affinity IIIa/b receptorFc fragment of IgG low affinity IIIb receptorFc gamma receptor III A/BFCG2AFcGRFCGR2A/BFCGR3FCGR3A/BFc gamma RIIa/b
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
PE
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.