For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30857F
Staining of C57BL/6 murine splenocytes with APC Anti-Mouse CD8a Antibody and PE Anti-Mouse CD226 Antibody[10E5] (left) or PE Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.
CD226 (DNAM-1) is constitutively expressed on native CD8+ cells and on CD4+ T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40% of inactivated CD4+ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.
Immunogen Information
Gene ID
225825
Synonyms
DNAM-1PTA1 (platelet and T cell activation antigen 1)TLISA1LFA-1 associated Molecule PTA-1
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
PE
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
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