C57BL/6 murine splenocytes are stained with Anti-Mouse CD28 Monoclonal Antibody(PE Conjugated)[Used at 0.02 μg/106 cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.
Immunogen Information
Gene ID
12487
Swissprot
P31041
Synonyms
T-cell-specific surface glycoprotein CD28Cd28CD28
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
PE
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.