PE Anti-Mouse CD90.2 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD21084F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD90.2 Monoclonal Antibody(PE Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
C57BL/6 murine splenocytes are stained with Anti-Mouse CD90.2 Monoclonal Antibody(PE Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
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Overview

Circle
Product Name
PE Anti-Mouse CD90.2 Antibody
Catalog Number
RD21084F
Clonality
Monoclonal
Isotype
Rat IgG2b, κ
Host
Rat

Background

Circle
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

Immunogen Information

Circle
Gene ID
21838
Synonyms
Thy-1.2 membrane glycoproteinThy1.2Thy-1.2 antigenCD90.2Thy-1.2

Applications

Circle
Reactivity
Mouse
Tested Applications
FCM
Conjugation
PE
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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