For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30703F
Rat splenocytes are stained with APC Anti-Rat CD3 Antibody and PE Anti-Rat CD161 Antibody (Left). Splenocytes are stained with APC Anti-Rat CD3 Antibody and PE Mouse IgG1, κ Isotype Control (Right).
CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor.
Immunogen Information
Gene ID
362443
Synonyms
NKR-P1CD161a/CD161bNKR-P1a/KLRB1a
Applications
Reactivity
Rat
Tested Applications
FCM
Conjugation
PE
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
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