Human peripheral blood lymphocytes are stained with Anti-Human CD45RO Monoclonal Antibody(FITC Conjugated) and Anti-Human CD123 Monoclonal Antibody(PE/Cyanine5 Conjugated)
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Overview
Product Name
PE/Cyanine5 Anti-Human CD123 Antibody
Catalog Number
RD21445F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.