Human peripheral blood lymphocytes are stained with FITC Anti-Human CD3 Antibody and PE/Cyanine5 Anti-Human CD19 Antibody (Left). Lymphocytes are stained with FITC Anti-Human CD3 Antibody and PE/Cyanine5 Mouse IgG1, κ Isotype Control (Right).
CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.