PE/Cyanine5 Anti-Rat CD44H Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD22290F
Rat splenocytes are stained with Anti-Rat CD44H Monoclonal Antibody(PE/Cyanine5 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Product Name
PE/Cyanine5 Anti-Rat CD44H Antibody
Catalog Number
RD22290F
Clonality
Monoclonal
Isotype
Mouse IgG2a, κ
Host
Mouse
Background
CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.
Immunogen Information
Gene ID
12505
Swissprot
P26051
Synonyms
Pgp-1H-CAMCD44sCD44H
Applications
Reactivity
Rat
Tested Applications
FCM
Conjugation
PE/Cyanine5
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.