PE/Cyanine5 Anti-Rat CD45 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD22306F
Rat splenocytes are stained with Anti-Rat CD45 Monoclonal Antibody(PE/Cyanine5 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Product Name
PE/Cyanine5 Anti-Rat CD45 Antibody
Catalog Number
RD22306F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.
Immunogen Information
Gene ID
19265
Swissprot
P04157
Synonyms
Receptor-type tyrosine-protein phosphatase CLeukocyte common antigenLCAT200Ly-5Ptprc
Applications
Reactivity
Rat
Tested Applications
FCM
Conjugation
PE/Cyanine5
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.