Human peripheral blood lymphocytes are stained with FITC Anti-Human CD3 Antibody and PE/Cyanine7 Anti-Human CD101 Antibody[BB27] (Left). Lymphocytes are stained with FITC Anti-Human CD3 Antibody and PE/Cyanine7 Mouse IgG1, κ Isotype Control (Right).
CD101 is a type I transmembrane glycoprotein, known as V7, and P126. It is a 120 kD homodimer, the member of EWI family within Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs posses higher inhibitory function. The biological function of CD101 is still not clear. But it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production.
Immunogen Information
Synonyms
V7P126
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
PE/Cyanine7
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Do not freeze.