PE/Cyanine7 Anti-Human CD20 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD22244F
Human peripheral blood lymphocytes are  stained with Anti-Human CD20 Monoclonal Antibody(PE/Cyanine7 Conjugated)(filled gray histogram) or Mouse IgG2b Isotype Control PE/Cy7(empty black histogram).
Human peripheral blood lymphocytes are stained with Anti-Human CD20 Monoclonal Antibody(PE/Cyanine7 Conjugated)(filled gray histogram) or Mouse IgG2b Isotype Control PE/Cy7(empty black histogram).
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Overview

Circle
Product Name
PE/Cyanine7 Anti-Human CD20 Antibody
Catalog Number
RD22244F
Clonality
Monoclonal
Isotype
Mouse IgG2b, κ
Host
Mouse

Background

Circle
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Immunogen Information

Circle
Gene ID
931
Swissprot
P11836
Synonyms
Bp35Leukocyte surface antigen Leu-16MS4A1B-lymphocyte surface antigen B1

Applications

Circle
Reactivity
Human
Tested Applications
FCM
Conjugation
PE/Cyanine7
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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