Human peripheral blood lymphocytes are stained with Anti-Human CD5 Monoclonal Antibody(PE/Cyanine7 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.