CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.
Immunogen Information
Gene ID
17086
Swissprot
Q8C567
Synonyms
Ly94mAR-1NK-p46mNKp46Lymphocyte antigen 94
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
PE/Cyanine7
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.