C57BL/6 murine bone marrow cells are stained with Anti-Mouse Ly6C Monoclonal Antibody(PercP Conjugated)[Used at 0.2 μg/106 cells dilution](filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control.
Most hematopoietic cells express one or more members of Ly-6 family. The expression of Ly-6 varies with development stage and activation. Ly-6C is a 14-17 kD GPI-linked surface protein expressed on mouse monocyte/macrophage cells, endothelial cells, neutrophils, and some T cell subsets. Ly-6C is reported to be an indicator of memory CD8+ T cells.