PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30674F
Human peripheral blood are stained with FITC Anti-Human CD11b Antibody and PerCP/Cyanine5.5 Anti-Human CD163 Antibody (Left). Cells in the monocyte gate were used for analysis. Cells are stained with FITC Anti-Human CD11b Antibody and PerCP/Cyanine5.5 Mouse IgG1,κ Isotype Control (Right).
Variation
Quantity
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Overview
Product Name
PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61]
Catalog Number
RD30674F
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
Immunogen Information
Gene ID
9332
Synonyms
GHI/61M130RM3/1p155Hemoglobin/Haptoglobin Complex Receptormacrophage-associated antigenED2(rat)
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
PerCP/Cyanine5.5
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.