PerCP/Cyanine5.5 Anti-Rat CD45 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD22312F
Rat splenocytes are  stained with Anti-Rat CD45 Monoclonal Antibody(PerCP/Cyanine5.5 Conjugated)[Used at 0.2 μg/10<sup>6</sup> cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Rat splenocytes are stained with Anti-Rat CD45 Monoclonal Antibody(PerCP/Cyanine5.5 Conjugated)[Used at 0.2 μg/106 cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
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Overview

Circle
Product Name
PerCP/Cyanine5.5 Anti-Rat CD45 Antibody
Catalog Number
RD22312F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse

Background

Circle
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

Immunogen Information

Circle
Gene ID
19265
Swissprot
P04157
Synonyms
Receptor-type tyrosine-protein phosphatase CLeukocyte common antigenLCAT200Ly-5Ptprc

Applications

Circle
Reactivity
Rat
Tested Applications
FCM
Conjugation
PerCP/Cyanine5.5
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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