PERK Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79226A
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PERK Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human brain tissue using PERK Polyclonal Antibody at dilution 1:50
Product Name
PERK Polyclonal Antibody
Catalog Number
RD79226A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Immunogen Information
Immunogen
Synthetic peptide of human EIF2AK3
Swissprot
Q9NZJ5
Synonyms
DKFZp781H1925E2AK3EC 2.7.11.1Eif2ak3Eukaryotic translation initiation factor 2 alpha kinase 3Eukaryotic translation initiation factor 2-alpha kinase 3Heme regulated EIF2 alpha kinaseHRIHsPEKPancreatic eIF2 alpha kinasePancreatic eIF2-alpha kinas
Gene Accession
NP_002657
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas