PFKM Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252666A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PFKM Polyclonal Antibody at dilution of 1:50(×200)
Product Name
PFKM Polyclonal Antibody
Catalog Number
RD252666A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Immunogen Information
Immunogen
Fusion protein of human PFKM
Swissprot
P08237
Synonyms
6 Phosphofructokinase Muscle Type6-phosphofructokinase6-phosphofructokinase muscle typeEC 2.7.1.1EC 2.7.1.11GSD7K6PFMGC8699muscle typePFKmuscle typePFK-APFKAPFKLPFKMPFKPPFKXPhosphofructo 1 Kinase Isozyme APhosphofructo-1-kinase isozyme A
Gene Accession
BC021203
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas