PFKM Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using PFKM Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PFKM Polyclonal Antibody at dilution of 1:50(×200)
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

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Product Name
PFKM Polyclonal Antibody
Catalog Number
RD252666A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

Immunogen Information

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Immunogen
Fusion protein of human PFKM
Swissprot
P08237
Synonyms
6 Phosphofructokinase Muscle Type6-phosphofructokinase6-phosphofructokinase muscle typeEC 2.7.1.1EC 2.7.1.11GSD7K6PFMGC8699muscle typePFKmuscle typePFK-APFKAPFKLPFKMPFKPPFKXPhosphofructo 1 Kinase Isozyme APhosphofructo-1-kinase isozyme A
Gene Accession
BC021203

Applications

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Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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