The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2
Immunogen Information
Immunogen
Recombinant protein of human PFKP
Swissprot
Q01813
Synonyms
1200015H23Rik6 phosphofructokinase type C6 phosphofructokinaseplatelet type6-phosphofructokinase6-phosphofructokinase type C9330125N24RikFLJ40226K6PPK6PPMGC105718PFK CPFKfibroblast typePFK-CPFKFPFKPPhosphofructo 1 kinase isozyme CPhospho
Calculated MW
86 kDa
Gene Accession
BC002536
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4