This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.
Immunogen Information
Immunogen
Synthetic peptide of human PFN1
Swissprot
P07737
Synonyms
Actin binding proteinALS18Epididymis tissue protein Li 184aOTTHUMP00000125244PFN 1PfnPFN1PROF1Profilin IProfilin-1Profilin1ProfilinI
Calculated MW
15 kDa
Gene Accession
NP_005013
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4