PFN2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of Human fetal brain tissue using PFN2 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human brain using PFN2 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human liver cancer using PFN2 Polyclonal Antibody at dilution of 1:30
Product Name
PFN2 Polyclonal Antibody
Catalog Number
RD76407A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Immunogen Information
Immunogen
Synthetic peptide of human PFN2
Swissprot
P35080
Synonyms
D3S1319EPFLPFN 2Pfn2PROF2Profilin IIProfilin-2Profilin2ProfilinII
Calculated MW
15 kDa
Gene Accession
NP_444252
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas