UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm . And UCHL1 is a Parkinson's disease susceptibility gene .
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse PGP9.5
Swissprot
P09936,Q9R0P9,Q00981
Synonyms
Epididymis luminal protein 117Epididymis secretory protein Li 53HEL 117HEL S 53NDGOANeuron cytoplasmic protein 9.5OTTHUMP00000218137OTTHUMP00000218139OTTHUMP00000218140OTTHUMP00000218141Park 5PARK5PGP 9.5PGP9.5PGP95Protein gene product 9.5
Calculated MW
27 kDa
Observed MW
27 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:300-1:800
Concentration
1.8 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4