PGR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70330A
Immunohistochemistry analysis of paraffin-embedded human endometrial cancer using PGR Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse uterus using PGR Polyclonal Antibody at dilution of 1:400.
Product Name
PGR Polyclonal Antibody
Catalog Number
RD70330A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
PGR,also named as NR3C3 and PR,belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Progesterone receptor
Swissprot
P06401,Q00175,Q63449
Synonyms
NR3C3Nuclear receptor subfamily 3 group C member 3PGRPRPRAPRBPRGRProgesterone receptorProgestin receptor form AProgestin receptor form B
Applications
Reactivity
Human,Mouse
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:800
Concentration
1.32 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.