Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
Immunogen Information
Immunogen
Recombinant fusion protein of human PHF20
Gene ID
51230
Swissprot
Q9BVI0
Synonyms
PHF20C20orf104GLEA2HCA58NZFTDRD20ATZP
Calculated MW
187kDa/192kDa
Observed MW
192kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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