This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.
Immunogen Information
Immunogen
Fusion protein of human PHF5A
Swissprot
Q7RTV0
Synonyms
1110007B08RikAc2 246bK223H9.2INIMGC1346OTTHUMP00000198827PHD finger 5aPHD finger like domain containing protein 5APHD finger like domain protein 5APHD finger protein 5APHD finger-like domain protein 5APHD finger-like domain-containing protein