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Overview
Product Name
PHLPP1 Polyclonal Antibody
Catalog Number
RD85334A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
Immunogen Information
Immunogen
Recombinant fusion protein of human PHLPP1 (NP_919431.2).