Phospho-HDAC5 (Ser498) Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85858A
Western Blot analysis of VEC cells with Phospho-HDAC5 (Ser498) Polyclonal Antibody at dilution of 1:500
Product Name
Phospho-HDAC5 (Ser498) Polyclonal Antibody
Catalog Number
RD85858A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
Immunogen Information
Immunogen
Synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498
Swissprot
Q9UQL6
Synonyms
Antigen NY CO 9Antigen NY-CO-9HD5HDAC 5HDAC5HDAC5Histone deacetylase 5NY CO 9
Calculated MW
122 kDa
Observed MW
122 kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.