Phospho-P38 (Thr180/Tyr182) Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85950A
Western Blot analysis of various cells with Phospho-p38 (Thr180/Tyr182) Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human colon tissue with Phospho-p38 (Thr180/Tyr182) Polyclonal Antibody at dilution of 1:200
Immunofluorescence analysis of Mouse liver tissue with Phospho-p38 (Thr180/Tyr182) Polyclonal Antibody at dilution of 1:200
Product Name
Phospho-P38 (Thr180/Tyr182) Polyclonal Antibody
Catalog Number
RD85950A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
Immunogen Information
Immunogen
Synthesized peptide derived from human p38 around the phosphorylation site of Thr180/Tyr182
Swissprot
Q16539
Synonyms
CSAID Binding Protein 1CSAID binding proteinCSAID-binding proteinCsaids binding proteinCSBP 1CSBP 2CSBPCSBP1CSBP2CSPB1Cytokine suppressive anti-inflammatory drug-binding proteinEXIPMAP kinase 14MAP kinase MXI2MAP kinase p38 alphaMAPK 14MAP
Calculated MW
41 kDa
Observed MW
38 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:5000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas