Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STA
Immunogen Information
Immunogen
Synthesized peptide derived from human Stat2 around the phosphorylation site of Tyr690
Swissprot
P52630
Synonyms
Homo sapiens interferon alpha induced transcriptional activatorinterferon alpha induced transcriptional activatorISGF 3ISGF3MGC59816P113signal transducer and activator of transcription 2 113kDSignal transducer and activator of transcription 2STAT1
Calculated MW
98 kDa
Observed MW
113 kDa
Applications
Reactivity
Human,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4